Description
Process Development Engineer - Biologics
APC Ltd is an award-winning and rapidly growing science- and technology-driven pharmaceutical process research company. In the space of 5 years, we have pioneered innovation in the sector and we now partner with 8 of the top-10 pharma and 5 of the top-10 biotech firms in the world.
From our world-class facility, we offer specialised chemical and process engineering solutions. Powered by novel technology and world-class scientific research, we help companies accelerate the development & launch of their medicines.
Our rapid growth has come from a commitment to excellence, a drive to innovate and the desire to develop a challenging, creative, and rewarding environment for our team. If you are interested in a career focused on technical innovation, technology design and impact, we would love to hear from you.
About the team
Department: Technical Operations
Reports to: Engineering Functional Lead/designee
Our Engineering team comprises of highly qualified, capable, and welcoming colleagues. We support our clients by delivering world class pharmaceutical process research and development to accelerate the delivery of quality, life-changing medicines to the patient across a wide range of therapeutic areas. Now more than ever the opportunities are greater as technology enhances our capability to make a real difference to patients.
Our team vision is to enhance the process development experience for our clients in a dynamic and cross-collaborative environment, with application of best-in-class bioprocess engineering techniques, modelling workflows, and technologies.
If you are looking to further your career in a cutting-edge dynamic, creative, and patient focussed environment then APC is for you.
Principal Duties and Objectives
- Work with multi-disciplinary research team to support the planning, organising and delivery of R&D biopharmaceutical process development programmes.
- Develop biopharmaceutical scale-up and optimisation strategies through application of engineering workflows and modelling tools which support the successful tech transfer of the final product to our partners.
- Design and establish scale-down models for bioprocess unit operations to understand and optimise manufacturing scale operations.
- Prepare and review technical presentations and report material, and present the issues, results and project progress to clients as required.
- Demonstrate the use of problem-solving skills requiring the application of engineering principles, calculations, and computational methods in approaching technical challenges.
- Adopt, maintain, and improve on APC’s engineering workflows and their incorporation into the day-to-day execution of commercial research projects and internal innovation strands.
- Ensure that operation to GLP standard within a R&D laboratory is always maintained.
- Support the execution of commercial and innovation R&D projects using engineering modelling tools such as CFD, Matlab, Python, MVDA, Dynochem etc.
- Solve complex technical problems and take responsibility for implementing the solutions using an Engineering first approach.
- Author and review technical reports.
- Ensure that safe working practices are adhered to in line with relevant local and legal requirements.
- Liaise with the Laboratory Coordinator, Facilities Supervisor, Area Owners and Equipment Owners as required to maintain a shared awareness of the issues requiring attention within the laboratories.
- Where applicable, coach mentor and train junior team members.
Minimum Requirements
- PhD in Chemical or Bio Engineering or related area; or Msc in Chemical or Bio Engineering or related area; or Bachelors in Chemical or Bio Engineering or related area.
- Minimum of 1-2+ years industry experience in pharmaceutical and/or biopharmaceutical process research and development.
- Experience in pharmaceutical /biopharmaceutical Engineering
- Ability to work in a dynamic and multidisciplinary environment
- Self-motivated with demonstrated project management skills
- Excellent technical communications skills, with previous technical presentation experience
- Ability to disseminate information to research team, and key stakeholders
Desirable Skills
- Proficient in PAT for the development of pharmaceutical/Bio Pharmaceutical processes (FBRM, ATR-FTIR, Raman etc)
- Experience in the use of statistical analysis and data driven computational methods
- Skilled in lab techniques (Aseptic)
- Hands on experience and subject matter expertise across USP and/or DSP bioprocess unit operations.
- Good understanding of DoE and QbD for process development
- Experience with scale-up techniques for processes from laboratory to plant scale
- Background and grounding in MATLAB, DynoChem, Python, CFD, MVDA and JMP.
How to apply
Suitable candidates should submit a CV and a Cover Letter by close of business 13th June 2025
APC is committed to the principle of equal opportunity for all employees. All employment decisions at APC are based on business needs, job requirements and individual qualifications, without regard to gender, ethnicity, age, religious belief, disability, sexual orientation, gender identity and/or expression, marital status, or any other status protected by Irish law.
Similar vacancies arising in the coming 6 months may be filled from this group of applicants.