Description
Senior Process Development Engineer - Digital
APC Ltd is an award-winning and rapidly growing science- and technology-driven pharmaceutical process research company. In the space of 5 years, we have pioneered innovation in the sector and we now partner with 8 of the top-10 pharma and 5 of the top-10 biotech firms in the world.
From our world-class facility, we offer specialised chemical and process engineering solutions. Powered by novel technology and world-class scientific research, we help companies accelerate the development & launch of their medicines.
Our rapid growth has come from a commitment to excellence, a drive to innovate and the desire to develop a challenging, creative, and rewarding environment for our team. If you are interested in a career focused on technical innovation, technology design and impact, we would love to hear from you.
About the team
Department: Technical Operations
Reports to: Technical Lead - Digital Engineering
Our Digitalization Engineering team comprises of highly qualified, capable, and welcoming colleagues. We support our clients by delivering world class pharmaceutical process research and development to accelerate the delivery of quality, life-changing medicines to the patient across a wide range of therapeutic areas. Now more than ever the opportunities are greater as technology enhances our capability to make a real difference to patients.
Our team vision is to enhance the process development experience for our clients in a dynamic and collaborative environment, with application of best-in-class chemical engineering techniques, modelling workflows, smart experimentation, and technologies.
If you are looking to further your career in a cutting-edge dynamic, creative, and patient focussed environment then APC is for you.
Principal Duties and Objectives
- Lead the technical delivery of R&D pharmaceutical and/or biopharmaceutical projects, ensuring excellence in execution. Oversee experimental workplans in line with APC’s Digital Engineering workflows, collaborating with engineers and scientists to develop innovative, effective solutions.
- Utilize advanced engineering workflows and modelling tools (e.g., CFD, Matlab, Python, R/Shiny, gProms, MVDA, Dynochem) to develop robust, safe and sustainable pharmaceutical and biopharmaceutical processes. Facilitate successful technology transfer and develop scaled-down process models for laboratory and simulation-based optimization and troubleshooting experiments.
- Solve complex technical challenges using engineering principles, computational methods, and data-driven insights, driving an Engineering-first mindset.
- Deliver clear, well-structured technical presentations and reports, effectively communicating project progress and results to clients. Ensure high quality documentation, including electronic lab book records.
- Develop and implement new digital engineering techniques and workflows to enhance project outcomes and business effectiveness. Contribute to APC’s continuous improvement initiatives.
- Maintain and improve on APC’s engineering workflows, ensuring seamless integration into commercial research projects and internal innovation programmes.
- Mentor, coach and train junior team members, fostering a culture of professional growth, collaboration and continuous learning.
Laboratory Duties
- Provide R&D laboratory support across APC’s Small and/or Large Molecule portfolios by collaborating with scientists, analysts, and engineer, both internally and externally.
- Conduct process development activities for Small and/or Large Molecule reaction and purification unit operations.
- Ensure adherence to GLP standards within the R&D laboratory and maintain a consistently high level of operational excellence.
- Ensure that safe working practices are adhered to in compliance with relevant local and legal safety requirements.
- Liaise with the Laboratory Coordinator, Facilities Supervisor, Area Owners and Equipment Owners as required to ensure shared awareness and resolution of laboratory issues requiring attention.
Minimum Requirements
- PhD in Chemical or Bio Engineering or related area; or Master’s in Chemical or Bio Engineering or related area; or Bachelor’s in Chemical or Bio Engineering or related area.
- Minimum of 3+ years industry experience in pharmaceutical process research and development (if PhD qualified); or Minimum of 5+ years industry experience (if Masters qualified); or Minimum of 7+ years industry experience (if Bachelors qualified).
- Experience in the use of statistical analysis and data driven computational methods, and engineering simulations tools (for e.g. CFD, Matlab, Python, R/Shiny, gProms, MVDA, Dynochem).
- Ability to thrive in a dynamic, multidisciplinary environment.
- Self-motivated with demonstrated project management skills.
- Excellent technical communications and presentation abilities.
- Capable of effectively disseminating information to research team and leadership.
Desirable Skills
- People management experience.
- Proficient in PAT for the development of pharmaceutical and/or biopharmaceutical processes (for e.g. tools such as FBRM, ATR-FTIR, Raman spectroscopy).
- Proficient in working across various engineering unit ops for pharmaceutical and/or biopharmaceutical process (for e.g. crystallization, drying, TFF, chromatography).
- Extensive experience in DoE and QbD methodologies for process development.
- Experience with scale-up techniques for processes from laboratory to plant scale.
How to apply
Suitable candidates should submit a CV and a Cover Letter by close of business 30th April 2025.
APC is committed to the principle of equal opportunity for all employees. All employment decisions at APC are based on business needs, job requirements and individual qualifications, without regard to gender, ethnicity, age, religious belief, disability, sexual orientation, gender identity and/or expression, marital status, or any other status protected by Irish law.
Similar vacancies arising in the coming 6 months may be filled from this group of applicants.
Salary
The salary is negotiable and dependent on the experience of the successful candidate.